Which other compound shares a similar phosphoryl transfer potential to ATP?

Prepare for the UofT BCH210H1 Biochemistry I midterm with exam-like questions. Access detailed solutions and explanations for proteins, lipids, and metabolism topics. Strengthen your understanding and excel on test day!

GTP (Guanosine triphosphate) shares a similar phosphoryl transfer potential to ATP (Adenosine triphosphate) due to its structure and the high-energy bonds present in both molecules. Both ATP and GTP contain three phosphate groups linked by high-energy phosphoanhydride bonds. When these bonds are hydrolyzed, they release a significant amount of energy, which can be used for various cellular processes.

The phosphoryl transfer potential of a nucleotide is determined by its ability to donate a phosphate group to another molecule, typically forming a high-energy intermediate. GTP can serve as an energy source for various biosynthetic reactions, protein synthesis, and signal transduction in a manner analogous to ATP.

While AMP, ADP, and PPi are related to cellular energy, their phosphoryl transfer potentials are not as high as that of ATP or GTP because they either contain fewer phosphate groups (like AMP) or have different energetic characteristics (such as PPi, which can be hydrolyzed to drive reactions but does not serve as a primary energy carrier in the same way). Thus, GTP is the correct choice as it mirrors ATP's energy transfer capabilities effectively.

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