What type of bond creates triglycerides from fatty acids?

Prepare for the UofT BCH210H1 Biochemistry I midterm with exam-like questions. Access detailed solutions and explanations for proteins, lipids, and metabolism topics. Strengthen your understanding and excel on test day!

Triglycerides are formed through a biochemical process called esterification, where three fatty acid molecules react with one glycerol molecule. This reaction involves the formation of ester bonds, which are created when the hydroxyl group (-OH) from the glycerol reacts with the carboxylic acid group (-COOH) of a fatty acid. During this process, a molecule of water is released for each fatty acid added, resulting in the formation of a triester – the triglyceride.

The ester bond is characterized by a linkage of the carbon atom of a carbonyl group to an oxygen atom, which in this case connects the glycerol backbone to the fatty acids. This bond is crucial, as it determines the properties of triglycerides, making them hydrophobic and a significant form of energy storage in living organisms.

Other options do not apply to the formation of triglycerides: phosphodiester bonds are found in nucleic acids; glycosidic bonds link sugars together; and hydrogen bonds occur between molecules due to affinity between polar groups but do not create covalent bonds necessary for forming triglycerides.

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