What is the physiological pH value typically observed in the human body?

Prepare for the UofT BCH210H1 Biochemistry I midterm with exam-like questions. Access detailed solutions and explanations for proteins, lipids, and metabolism topics. Strengthen your understanding and excel on test day!

In the human body, the physiological pH value is typically around 7.4, which is slightly alkaline. This pH range is crucial for maintaining various biochemical processes, including enzyme activity, metabolic functions, and the overall homeostasis of bodily fluids.

The body has several mechanisms in place to regulate pH, including buffer systems such as bicarbonate, phosphate, and proteins, which counteract changes in acidity or alkalinity. A pH of 7.4 allows enzymes to function optimally, as most enzymes have a specific pH range in which they exhibit maximum activity. Deviations from this pH can lead to metabolic disturbances and can compromise the function of critical biological processes.

The other values presented are not in line with the typical physiological pH. A pH of 6.4 is too acidic and would be detrimental to human health, leading to acidosis. A pH of 7.0 is neutral and does not accurately reflect the body's slightly alkaline state. A pH of 8.0 is too basic, which can lead to alkalosis and disrupt normal metabolic functions. Therefore, the normal physiological pH of 7.4 is essential for maintaining health and ensuring that biochemical reactions proceed efficiently in the body

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