What is the backbone structure of sphingolipids?

Prepare for the UofT BCH210H1 Biochemistry I midterm with exam-like questions. Access detailed solutions and explanations for proteins, lipids, and metabolism topics. Strengthen your understanding and excel on test day!

The backbone structure of sphingolipids is based on sphingosine, which is an amino alcohol that serves as the foundational scaffold for this class of lipids. Sphingolipids are distinct from other lipid types, as they do not utilize glycerol as their backbone like triglycerides and phospholipids do. Instead, sphingosine provides a unique structure that contributes to the functional diversity of sphingolipids.

Sphingolipids often consist of a sphingosine backbone that is linked to a fatty acid via an amide bond, forming a ceramide. This ceramide can further associate with various head groups, such as phosphocholine or sugars, to form different classes of sphingolipids, such as sphingomyelin and glycosphingolipids.

The other options represent different classes of lipids or structures: glycerol is the backbone of triglycerides and phospholipids, cholesterol is a steroid and does not serve as a backbone in sphingolipids, and fatty acids are components that can be attached to other molecules but are not backbone structures in sphingolipids. Therefore, the choice highlighting the sphingosine backbone accurately reflects the structural foundation

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