Can facilitated diffusion be described as saturable?

Prepare for the UofT BCH210H1 Biochemistry I midterm with exam-like questions. Access detailed solutions and explanations for proteins, lipids, and metabolism topics. Strengthen your understanding and excel on test day!

Facilitated diffusion can indeed be described as saturable because it involves specific transport proteins that help molecules move across a membrane down their concentration gradient. When the substrate concentration is low, the transport proteins can effectively bind and transport the molecules, leading to a linear relationship between the substrate concentration and the rate of diffusion. However, as the substrate concentration increases and approaches a saturation point, the transport proteins become fully occupied, and no additional increase in transport can occur, regardless of further increases in substrate concentration. This saturation effect indicates that there is a maximum rate of transport that can be achieved, which is characteristic of facilitated diffusion. Thus, at high substrate concentrations, the system reaches saturation, confirming that facilitated diffusion is indeed a saturable process.

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